INJECTABLE ANESTHETICS IN SWINE

SEDATION
Acepromazine Ketamine	0.5 mg/kg IM 15 mg/kg IM	Good sedation, unreliable for surgery Give acepromazine at least 10 minutes prior to ketamine
Diazepam Ketamine	0.5-2 mg/kg IM 10-15 mg/kg IM	Sedation only Good muscle relaxation
Xylazine Ketamine	1-2 mg/kg IM 5-10 mg/kg IM IV (for induction prior to inhalant anesthesia)	Moderate sedation at low doses, deep sedation at high doses Good relaxation Use ¼ to ½ dose for induction prior to inhalant anesthesia
Detomidine Butorphenol Midazolam	0.06 mg/kg IM 0.3 mg/kg IM 0.3 mg/kg IM	Sedation only; extremely expensive
Azaperaone	0.5 mg/kg 2-8 mg/kg 5-10 mg/kg	Mixing of pigs Sedations Knock-down

ANESTHESIA
Telazol®	1-5 mg/kg IM	Sedation at low doses, anesthesia at high doses Poor muscle relaxation, intubation difficult Prolonged recovery at high doses (link to video)
Xylazine Telazol®	0.5-2.2 mg/kg IM 3-6 mg/kg IM	Anesthesia with good analgesia and muscle relaxation. Intubation possible. Apnea may occur.
Telazol® Ketamine } TKX Xylazine	4.4 mg/kg IM 2.2 mg/kg IM 2.2 mg/kg IM IV (for induction prior to inhalant anesthesia) – give slowly (over 1min) to reduce respiratory depression	Reconstitute powdered Telazol® with 250mg xylazine (2.5ml) and 250mg ketamine (2.5ml). Dose at 1ml/25-35kg (use 1 ml/ 75kg for IV induction) Intubation possible, apnea may occur. Duration: 45-90 minutes
Guifenesin Ketamine Xylazine (“Triple Drip”)	IV infusion Induction: 0.6-1 ml/kg CRI : 2 – 2.5 ml/kg/hr	Mix to final concentration of 50mg/ml guafenesin, 2 mg/ml ketamine and 1 mg/ml xylazine Good for Cesearian sections because piglets are only minimally depressed
Propofol	IV infusion Induction: 2-5 mg/kg CRI : 4-8 mg/kg/hr	Rapid onset, short duration, short, smooth recovery Apnea common, intubation recommended